Purity ≥ 99%MOTS-c
Mitochondrial-derived peptideAnalytical-grade peptide reference material, supplied as a lyophilized powder for in-vitro laboratory research use only.
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Est. 2-5 days
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Overnight shipping available
Mitochondrial-derived peptide
MOTS-c
Analytical-grade peptide reference material, supplied as a lyophilized powder for in-vitro laboratory research use only.
Free shipping over $149 · CoA included with every order
Est. 2-5 days
Free shipment protection
Overnight shipping available
Secure checkout · cards processed by our payment provider
Lab Tested by Vanguard · Certificate of Analysis per lot
MOTS-c
MOTS-c is supplied as an analytical-grade biochemical reference material for laboratory research use only.
Intended use
Supplied for in-vitro research, analytical method development, identity verification, and laboratory evaluation by qualified research customers.
Restrictions
Not for human or animal consumption. Not for therapeutic, clinical, diagnostic, dietary-supplement, dosing, injection, ingestion, or administration use.
By ordering, the buyer confirms qualified research use and agrees not to use the material for human or animal consumption or administration. Refrigerate upon receipt; keep in a dark environment.
Published research
Selected peer-reviewed literature
Independent published studies on this compound, listed for research reference only. These citations are not claims of any effect; VNG materials are supplied for laboratory research use.
MOTS-c and metabolic disorders
Metabolites · PubMed ↗
MOTS-c and muscle-atrophy signaling
American journal of physiology. Endocrinology and metabolism · PubMed ↗
MOTS-c mitochondrial peptide — therapeutic overview
Frontiers in endocrinology · PubMed ↗
MOTS-c as a mitochondrial regulator of the nucleus
BioEssays : news and reviews in molecular, cellular and developmental biology · PubMed ↗
MOTS-c, metabolism & insulin resistance
Cell metabolism · PubMed ↗
MOTS-c and ovarian cancer — mechanism study
Advanced science (Weinheim, Baden-Wurttemberg, Germany) · PubMed ↗
MOTS-c and pulmonary fibrosis
Mitochondrion · PubMed ↗
MOTS-c and gestational diabetes
Pharmacological research · PubMed ↗
MOTS-c and bone metabolism
Frontiers in physiology · PubMed ↗
MOTS-c in aging and age-related disease
International journal of molecular sciences · PubMed ↗
Common questions
About this material
Answers describe what the published research examines and where the evidence is limited. They are not claims of any effect; this material is supplied for laboratory research use only.
What is MOTS-c?
MOTS-c is a small peptide of about 16 amino acids that is unusual because it is encoded inside mitochondrial DNA rather than the cell's nucleus. It belongs to a group called mitochondrial-derived peptides and is supplied here as an analytical-grade reference material for laboratory research use only.
Why is MOTS-c described as a 'mitochondrial-derived' peptide?
Almost all peptides are built from instructions in nuclear DNA, but MOTS-c is encoded within the mitochondrial 12S rRNA gene. That origin is a big part of the scientific interest, since it suggests mitochondria can send out their own signaling molecules to the rest of the cell.
Is MOTS-c supported by human clinical trials?
Not substantially. The published evidence is overwhelmingly preclinical -- cell cultures, animal models, and mechanistic or review articles -- with human data limited mostly to observational work on how MOTS-c levels relate to aging and metabolism. That is an important caveat when interpreting the research.
What do researchers study MOTS-c for?
Chiefly how cells manage and burn energy, how muscle responds to metabolic stress, and how mitochondrial signaling changes with aging. These are laboratory research questions about mechanism, not established uses in people.
How is VNG Labs' MOTS-c supplied and tested?
Melanotan II is provided as an analytical-grade, lyophilized reference material for laboratory research use only, with third-party testing (Vanguard) for identity and purity. It is not a drug or supplement and is not intended for human or veterinary use.
Full research overview: MOTS-c: What It Is and What It Does
Research stack
Frequently researched together
Reference materials commonly studied alongside MOTS-c in the published literature. Add the stack to your research order in one step. Supplied for laboratory research use only.
MOTS-c · 10mg
$79
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