Semax

Semax is a synthetic heptapeptide derived from a short, neuroactive fragment of the hormone ACTH, with an added proline-glycine-proline tail that makes it more stable. It is studied mainly for neuroprotection and cognition, and is supplied here as an analytical-grade reference material for laboratory research use only.

Semax was developed in Russia in the 1980s-1990s at the Russian Academy of Sciences and has been studied and used there as a nootropic and neuroprotective agent. Much of the published research originates from Russian laboratories.

Not by the standard most Western researchers would expect. The evidence provided here is entirely preclinical — animal and cell studies — and while Semax has a history of clinical use in Russia, large, independent, well-controlled human trials are lacking. That is an important caveat.

Semax copies a fragment of ACTH that acts on the nervous system but does not trigger the stress-steroid release the full hormone causes. So despite the hormonal origin, researchers study it as a brain-signaling peptide rather than a stress hormone.

Keep the lyophilized powder cold and dark, and refrigerate it after reconstitution with bacteriostatic water while avoiding repeated freeze-thaw cycles. See the storage note and reconstitution guide for specifics.