Copper tripeptide8 min read

GHK-Cu: What It Is and What It Does

A natural copper peptide that drops with age — a mainstay of skin, collagen, and wound-healing research. Below: what GHK-Cu is, what it does in plain terms, and the published studies — for laboratory research use only.

VNG Research TeamJuly 15, 2026
Class
Copper tripeptide
Published studies cited
10
Literature span
2012–2025

For research & educational purposes only. This article is a neutral, procedural reference for laboratory / in-vitro research handling — not medical advice or a usage recommendation. These materials are not for human or animal consumption.

On this page

What GHK-Cu is

GHK-Cu is a very small peptide that carries a copper atom, found naturally in your blood. Levels are high when you're young and fall as you age. It is supplied as an analytical-grade reference material for laboratory research.

What it does — in plain terms

GHK-Cu acts like a repair-and-maintenance signal for skin. In lab studies it appears to tell skin cells to make more collagen, clean up damaged tissue, and close wounds — the upkeep jobs the body does less of as it gets older. That's why it is one of the most-studied peptides in skin science and shows up across so much anti-aging and wound-healing research.

Here's where GHK-Cu actually shows up in the published research:

  • Collagen production in skin
  • Wound healing
  • Skin repair and anti-aging models
  • Switching specific genes on and off (gene expression)

Plain-language explanations describe what researchers study — not what any product does for a person, and not medical advice. Every material here is sold for laboratory research use only and is not for human or animal use.

Reconstitution reference

Standard laboratory reconstitution volumes for GHK-Cu, from the VNG Reconstitution Sheet. See the full reconstitution guide for the method and concentration math.

ProductVialBacteriostatic waterResulting concentration
GHK-Cu50 mg1.5 mL~33.3 mg/mL
GHK-Cu100 mg3 mL~33.3 mg/mL
GLOW (GHK-Cu + BPC-157 + TB-500)70 mg3 mL~23.3 mg/mL
KLOW (BPC-157 + GHK-Cu + TB-500 + KPV)80 mg3 mL~26.7 mg/mL

Published research

A selection of peer-reviewed and clinical literature indexed on PubMed. Provided so qualified researchers can locate the primary sources — inclusion here is not a claim about any product or outcome.

  1. Lab / formulation studyPharmaceutics · 2023

    GHK-Cu tripeptide in liposomes — cosmetic study

    View on PubMed
  2. Lab / formulation studyColloids and surfaces. B, Biointerfaces · 2025

    GHK-Cu microsphere filler — anti-inflammatory study

    View on PubMed
  3. Lab / formulation studyMolecules (Basel, Switzerland) · 2025

    GHK-Cu skin permeation in liposomes

    View on PubMed
  4. Peer-reviewed studyRedox biology · 2024

    GHK-Cu and lung inflammation / fibrosis

    View on PubMed
  5. Animal-model studyJournal of orthopaedic research : official publication of the Orthopaedic Research Society · 2015

    GHK-Cu and ACL healing — rat model

    View on PubMed
  6. Peer-reviewed studyOxidative medicine and cellular longevity · 2012

    GHK-Cu, oxidative stress & aging

    View on PubMed
  7. Peer-reviewed studyInternational journal of molecular sciences · 2020

    GHK copper-peptide complex — chemistry study

    View on PubMed
  8. Animal-model studyLife sciences · 2020

    GHK-Cu and pulmonary fibrosis — animal model

    View on PubMed
  9. Lab / formulation studyBiomaterials research · 2025

    Copper-tripeptide hydrogel and wound healing

    View on PubMed
  10. Lab / formulation studyBiomolecules · 2020

    Recombinant GHK tripeptide and copper toxicity — zebrafish

    View on PubMed

References & resources

Related reference materials

VNG Research Team

VNG Labs supplies analytical-grade reference materials with lot-matched Certificates of Analysis. Our write-ups are neutral, source-cited references for qualified and independent researchers.

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Research use only. Not for human consumption or veterinary use. Sold exclusively to qualified researchers for in vitro and laboratory research. These statements have not been evaluated by the FDA. Not intended to diagnose, treat, cure, or prevent any disease. Refrigerate upon receipt. Keep in dark environment.