Long-R3 IGF-1 analog8 min read

IGF-1 LR3: What It Is and What It Does

A longer-lasting 'grow and multiply' signal — a common tool in cell-culture research. Below: what IGF-1 LR3 is, what it does in plain terms, and the published studies — for laboratory research use only.

VNG Research TeamJuly 15, 2026
Class
Long-R3 IGF-1 analog
Published studies cited
10
Literature span
1992–2025

For research & educational purposes only. This article is a neutral, procedural reference for laboratory / in-vitro research handling — not medical advice or a usage recommendation. These materials are not for human or animal consumption.

On this page

What IGF-1 LR3 is

IGF-1 LR3 is a tweaked, longer-lasting version of a natural growth factor called insulin-like growth factor 1. It is supplied as an analytical-grade reference material for laboratory research.

What it does — in plain terms

IGF-1 is one of the body's main 'grow and multiply' signals for cells. The 'LR3' version is engineered to stay active much longer in lab conditions, which makes it convenient for experiments. In cell-culture research it's used to study how cells grow, divide, and respond to growth signals — it's a common tool for keeping cells growing steadily in a dish.

Here's where IGF-1 LR3 actually shows up in the published research:

  • Cell growth and division
  • The IGF growth-signal pathway
  • A working tool for cell-culture experiments

Plain-language explanations describe what researchers study — not what any product does for a person, and not medical advice. Every material here is sold for laboratory research use only and is not for human or animal use.

Reconstitution reference

Standard laboratory reconstitution volumes for IGF-1 LR3, from the VNG Reconstitution Sheet. See the full reconstitution guide for the method and concentration math.

ProductVialBacteriostatic waterResulting concentration
IGF-1 LR31 mg2 mL0.5 mg/mL

Published research

A selection of peer-reviewed and clinical literature indexed on PubMed. Provided so qualified researchers can locate the primary sources — inclusion here is not a claim about any product or outcome.

  1. Animal-model studyJournal of Alzheimer's disease : JAD · 2025

    IGF-1 LR3 and amyloid plaques — mouse model

    View on PubMed
  2. Animal-model studyDomestic animal endocrinology · 1999

    IGF-1 LR3 and protein metabolism — cattle

    View on PubMed
  3. Lab / formulation studyApplied microbiology and biotechnology · 2023

    Recombinant IGF-1 LR3 expression — lab study

    View on PubMed
  4. Animal-model studyThe Journal of endocrinology · 1997

    IGF-1 LR3 and growth markers — pigs

    View on PubMed
  5. Peer-reviewed studyGrowth factors (Chur, Switzerland) · 1996

    IGF-1 LR3 muteins — protein design study

    View on PubMed
  6. Peer-reviewed studyGrowth factors (Chur, Switzerland) · 2002

    IGF-1 LR3 and intestinal absorption

    View on PubMed
  7. Animal-model studyThe Journal of endocrinology · 1995

    IGF-1 LR3 and organ growth — guinea pig

    View on PubMed
  8. Animal-model studyEndocrine · 1998

    IGF-1 and bone-marrow cell development — mouse

    View on PubMed
  9. Mechanistic studyOncogene · 2007

    IGF binding protein-3 and prostate cancer — mechanism

    View on PubMed
  10. Lab / formulation studyEndocrinology · 1992

    IGF and IGF-binding proteins — ovarian cells

    View on PubMed

References & resources

Related reference materials

VNG Research Team

VNG Labs supplies analytical-grade reference materials with lot-matched Certificates of Analysis. Our write-ups are neutral, source-cited references for qualified and independent researchers.

More from Learn

Research use only. Not for human consumption or veterinary use. Sold exclusively to qualified researchers for in vitro and laboratory research. These statements have not been evaluated by the FDA. Not intended to diagnose, treat, cure, or prevent any disease. Refrigerate upon receipt. Keep in dark environment.