Purity ≥ 99%Melanotan II
alpha-MSH analogAnalytical-grade peptide reference material, supplied as a lyophilized powder for in-vitro laboratory research use only.
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Est. 2-5 days
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alpha-MSH analog
Melanotan II
Analytical-grade peptide reference material, supplied as a lyophilized powder for in-vitro laboratory research use only.
Free shipping over $149 · CoA included with every order
Est. 2-5 days
Free shipment protection
Overnight shipping available
Secure checkout · cards processed by our payment provider
Lab Tested by Vanguard · Certificate of Analysis per lot
Melanotan II
Melanotan II is supplied as an analytical-grade biochemical reference material for laboratory research use only.
Intended use
Supplied for in-vitro research, analytical method development, identity verification, and laboratory evaluation by qualified research customers.
Restrictions
Not for human or animal consumption. Not for therapeutic, clinical, diagnostic, dietary-supplement, dosing, injection, ingestion, or administration use.
By ordering, the buyer confirms qualified research use and agrees not to use the material for human or animal consumption or administration. Refrigerate upon receipt; keep in a dark environment.
Published research
Selected peer-reviewed literature
Independent published studies on this compound, listed for research reference only. These citations are not claims of any effect; VNG materials are supplied for laboratory research use.
Melanotan II — melanogenesis & skin pigmentation (phase I)
Life Sciences · PubMed ↗
Melanotan II and thermogenesis — mouse model
Experimental physiology · PubMed ↗
Melanotan II and feeding behavior — brain study
Neuropeptides · PubMed ↗
Melanotan II and diet-induced memory impairment
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · PubMed ↗
Melanotan II and cisplatin ototoxicity
Hearing research · PubMed ↗
Melanotan II melanocortin agonist — human studies
International journal of impotence research · PubMed ↗
Melanotan II and nerve regeneration — rat
European journal of pharmacology · PubMed ↗
Melanotan II and renal infarction — case review
CEN case reports · PubMed ↗
Melanotan II — qualitative forum study
Dermatology (Basel, Switzerland) · PubMed ↗
Use of melanotan I and II — population study
BMJ (Clinical research ed.) · PubMed ↗
Melanotan II and insulin sensitivity — rat model
Peptides · PubMed ↗
Common questions
About this material
Answers describe what the published research examines and where the evidence is limited. They are not claims of any effect; this material is supplied for laboratory research use only.
What is Melanotan II?
Melanotan II is a synthetic, ring-shaped analog of the pigment hormone alpha-MSH. Unlike Melanotan I, it activates several melanocortin receptors, giving it broad effects across pigment, appetite, and other systems. It is supplied here as an analytical-grade reference material for laboratory research use only.
How does it differ from Melanotan I?
Melanotan I is linear and acts fairly selectively on the pigment (MC1R) pathway; Melanotan II is cyclic and non-selective, engaging multiple melanocortin receptors. That makes Melanotan II more potent but also broader and less predictable in its effects.
Is Melanotan II an approved medicine?
No. Melanotan II has never been approved as a drug. A notable part of its research literature actually documents adverse effects and problems from unregulated use, which is an important caveat when interpreting it.
What is the connection to bremelanotide (PT-141)?
Research on Melanotan II's effects on the melanocortin system, including sexual-response pathways, helped motivate the development of bremelanotide, a separate and more receptor-selective peptide. Melanotan II itself remains an unapproved research compound.
How is it supplied and tested?
Melanotan II is supplied as a lyophilized powder for laboratory research use only, with identity and purity verified by third-party testing through Vanguard. It is not a cosmetic, drug, or supplement and is not intended for human or veterinary use.
Full research overview: Melanotan II: What It Is and What It Does
Research stack
Frequently researched together
Reference materials commonly studied alongside Melanotan II in the published literature. Add the stack to your research order in one step. Supplied for laboratory research use only.
Melanotan II · 10mg
$49
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