For research & educational purposes only. This article is a neutral, procedural reference for laboratory / in-vitro research handling — not medical advice or a usage recommendation. These materials are not for human or animal consumption.
What Melanotan II is
Melanotan II is a lab-made, ring-shaped copy of the pigment hormone alpha-MSH. It is supplied as an analytical-grade reference material for laboratory research.
What it does — in plain terms
Like Melanotan I, it mimics the signal that tells skin cells to make pigment — but its shape lets it hit more than one receptor, so the research on it is broader. Studies look at the melanocortin system: a family of 'switches' in the body that this hormone controls, of which pigment is just one. It's a tool for understanding how a single hormone can trigger several different responses.
Here's where Melanotan II actually shows up in the published research:
- Skin pigmentation
- The melanocortin-receptor system
- How one hormone can trigger several different signals
Plain-language explanations describe what researchers study — not what any product does for a person, and not medical advice. Every material here is sold for laboratory research use only and is not for human or animal use.
Reconstitution reference
Standard laboratory reconstitution volumes for Melanotan II, from the VNG Reconstitution Sheet. See the full reconstitution guide for the method and concentration math.
| Product | Vial | Bacteriostatic water | Resulting concentration |
|---|---|---|---|
| Melanotan II | 10 mg | 2 mL | 5 mg/mL |
Published research
A selection of peer-reviewed and clinical literature indexed on PubMed. Provided so qualified researchers can locate the primary sources — inclusion here is not a claim about any product or outcome.
- Human clinical studyLife Sciences · 1996
Melanotan II — melanogenesis & skin pigmentation (phase I)
View on PubMed - Animal-model studyExperimental physiology · 2021
Melanotan II and thermogenesis — mouse model
View on PubMed - Peer-reviewed studyNeuropeptides · 2022
Melanotan II and feeding behavior — brain study
View on PubMed - Animal-model studyBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2023
Melanotan II and diet-induced memory impairment
View on PubMed - Peer-reviewed studyHearing research · 2002
Melanotan II and cisplatin ototoxicity
View on PubMed - Peer-reviewed studyInternational journal of impotence research · 2000
Melanotan II melanocortin agonist — human studies
View on PubMed - Animal-model studyEuropean journal of pharmacology · 2003
Melanotan II and nerve regeneration — rat
View on PubMed - Peer-reviewed reviewCEN case reports · 2020
Melanotan II and renal infarction — case review
View on PubMed - Peer-reviewed studyDermatology (Basel, Switzerland) · 2021
Melanotan II — qualitative forum study
View on PubMed - Peer-reviewed studyBMJ (Clinical research ed.) · 2009
Use of melanotan I and II — population study
View on PubMed - Animal-model studyPeptides · 2004
Melanotan II and insulin sensitivity — rat model
View on PubMed
References & resources
Related reference materials
VNG Research Team
VNG Labs supplies analytical-grade reference materials with lot-matched Certificates of Analysis. Our write-ups are neutral, source-cited references for qualified and independent researchers.
More from LearnResearch use only. Not for human consumption or veterinary use. Sold exclusively to qualified researchers for in vitro and laboratory research. These statements have not been evaluated by the FDA. Not intended to diagnose, treat, cure, or prevent any disease. Refrigerate upon receipt. Keep in dark environment.
