Purity ≥ 99%SS-31
Mitochondrial-targeted tetrapeptideAnalytical-grade peptide reference material, supplied as a lyophilized powder for in-vitro laboratory research use only.
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Est. 2-5 days
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Mitochondrial-targeted tetrapeptide
SS-31
Analytical-grade peptide reference material, supplied as a lyophilized powder for in-vitro laboratory research use only.
Free shipping over $149 · CoA included with every order
Est. 2-5 days
Free shipment protection
Overnight shipping available
Secure checkout · cards processed by our payment provider
Lab Tested by Vanguard · Certificate of Analysis per lot
SS-31
SS-31 is supplied as an analytical-grade biochemical reference material for laboratory research use only.
Intended use
Supplied for in-vitro research, analytical method development, identity verification, and laboratory evaluation by qualified research customers.
Restrictions
Not for human or animal consumption. Not for therapeutic, clinical, diagnostic, dietary-supplement, dosing, injection, ingestion, or administration use.
By ordering, the buyer confirms qualified research use and agrees not to use the material for human or animal consumption or administration. Refrigerate upon receipt; keep in a dark environment.
Published research
Selected peer-reviewed literature
Independent published studies on this compound, listed for research reference only. These citations are not claims of any effect; VNG materials are supplied for laboratory research use.
Elamipretide (SS-31) improves ADP sensitivity in aged mitochondria by increasing uptake through the adenine nucleotide transporter
GeroScience · PubMed ↗
The mitochondria-targeted peptide SS-31 binds lipid bilayers and modulates surface electrostatics
The Journal of biological chemistry · PubMed ↗
Elamipretide: a review of its structure, mechanism of action, and therapeutic potential
International journal of molecular sciences · PubMed ↗
Mitochondria-targeted peptide SS-31 prevents cisplatin-induced acute kidney injury via the mitochondrial ROS–NLRP3 pathway
Biomedicine & pharmacotherapy · PubMed ↗
Common questions
About this material
Answers describe what the published research examines and where the evidence is limited. They are not claims of any effect; this material is supplied for laboratory research use only.
What is SS-31?
SS-31 is a synthetic four-amino-acid peptide designed to concentrate inside mitochondria, where it binds a membrane lipid called cardiolipin. It is supplied here as an analytical-grade reference material for laboratory research use only.
Is SS-31 the same as elamipretide?
Yes. SS-31 is the research name; elamipretide (also known as MTP-131) is the name used in clinical development. They refer to the same mitochondria-targeting peptide.
How does SS-31 reach the mitochondria?
Its alternating aromatic and positively charged amino acids let it cross membranes and accumulate on the inner mitochondrial membrane, binding cardiolipin. Notably, it does this without relying on the membrane's electrical charge, so it can still reach stressed mitochondria.
Is SS-31 supported by human clinical trials?
Only partly. Most published evidence is preclinical, from isolated mitochondria, cells, and animals. As elamipretide it has been tested in human trials for mitochondrial disease, but outcomes have been mixed and a clear benefit is not yet established.
How is VNG Labs' SS-31 supplied and tested?
SS-31 is provided as an analytical-grade, lyophilized reference material for laboratory research use only, with third-party testing (Vanguard) for identity and purity. It is not a drug or supplement and is not intended for human or veterinary use.
Full research overview: SS-31: What It Is and What It Does
SS-31 · 10mg
$99
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